What is the inactivated Japanese encephalitis vaccine?

Mar 22, 2022 Source: Cainiu Health
Disease description:

You also need to receive the Japanese encephalitis vaccine soon. There are two vaccine options available: what is the inactivated Japanese encephalitis vaccine?

Doctor's answer (1)
Dr. Ding Hongfang
The inactivated Japanese encephalitis vaccine is used to prevent epidemic Japanese encephalitis. Inactivated vaccines are produced by culturing pathogenic microorganisms and then inactivating them—i.e., eliminating their ability to replicate—using chemical or physical inactivation methods. During manufacturing, inactivating agents are employed to kill the pathogen and simultaneously eliminate potential contaminants introduced during production. However, the inactivation process may also damage key antigenic epitopes, potentially compromising immunogenicity; therefore, multiple doses are required to ensure adequate immune protection.