What are the possible abnormalities associated with double Y chromosomes?

Aug 24, 2022 Source: Cainiu Health
Disease description:

Examination revealed an abnormality in the double Y chromosome. What are the possible manifestations of a double Y chromosome abnormality?

Doctor's answer (1)
Dr. Wang Xueying
Symptoms of XYY chromosome syndrome often manifest as normal phenotype with tall stature, exceeding peers by 0–5 cm. The incidence increases with greater height; among males taller than 2 meters, the occurrence rate is 10%. Patients with XYY chromosome syndrome may present with radioulnar synostosis, severe acne, epileptic seizures, and cardiovascular abnormalities. Most patients have normal intelligence with IQ within the normal range, although a minority may experience delayed speech and language development. It is recommended that patients seek timely medical evaluation and appropriate treatment at a hospital to facilitate recovery.