What are the risks of elevated transaminase levels in cholecystitis?

Dec 26, 2022 Source: Cainiu Health
Disease description:

During a hospital check-up, the doctor told me I have cholecystitis with elevated transaminase levels. I would like to know what harm can be caused by high transaminase levels in cholecystitis.

Doctor's answer (1)
Dr. Shen Yonghua
Elevated transaminases caused by cholecystitis usually indicate impaired liver function. This may further lead to increased levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), and even alkaline phosphatase (ALP). Persistently elevated transaminases may suggest severe inflammation due to cholecystitis, indicating a more critical condition for the patient. Bacteria from the gallbladder may invade the liver via the biliary tract, causing liver dysfunction and increasing the risk of complications. For transaminase elevation caused by cholecystitis, prompt medical attention is necessary. Treatment may include dietary adjustments, antibiotics, choleretic agents, and hepatoprotective medications. If symptoms persist or worsen, surgical interventions such as laparoscopic cholecystectomy may be required. Additionally, patients should rest adequately and avoid strenuous physical activity to prevent additional strain on the liver.