Should patients with lupus nephritis due to systemic lupus erythematosus receive a kidney transplant?

Dec 26, 2022 Source: Cainiu Health
Disease description:

I have many red rashes on my body, severe pain, and multiple areas of ulceration. I also suffer from poor sleep quality and low energy. After examination, I was diagnosed with lupus nephritis. I would like to ask: does lupus nephritis require a kidney transplant?

Doctor's answer (1)
Dr. Liu Aihua
The decision to perform kidney transplantation in patients with lupus nephritis depends on the number of complications present. If only a single kidney is affected and other organ functions are normal, with lupus disease essentially under control, transplantation may be considered. However, when systemic lupus erythematosus involves significant damage to multiple organs, some experts recommend caution regarding kidney replacement. In cases where the underlying autoimmune disease is poorly controlled, graft survival is compromised, and immune rejection may adversely affect the function of the transplanted kidney, leading to reduced kidney survival rates.