Can lupus erythematosus spontaneously disappear within one hour and then recur the next day?

Lupus erythematosus typically does not spontaneously resolve within one hour and then recur the next day.

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the body's immune system mistakenly attacking its own tissues and organs, resulting in widespread inflammation and damage. Symptoms may include joint pain, skin rashes, fatigue, fever, and involvement of internal organs. Cutaneous manifestations of lupus, such as the malar rash, typically do not disappear spontaneously within one hour and then recur the following day. This disease is characterized by fluctuating symptoms and intermittent flare-ups; however, generally, the appearance and resolution of skin lesions last for a longer duration and require specific treatment for relief. Moreover, lupus flares do not follow a fixed temporal pattern; some patients may experience repeated episodes within a short period, while others may remain in prolonged clinical remission for years without recurrence. Lupus flares can be influenced by multiple factors, including adherence to treatment and the avoidance of triggers that may provoke disease activity. If patients discontinue or reduce their medication without medical guidance after improvement, or if they fail to avoid known triggers such as sun exposure, use of cosmetics, hair dyeing, cold exposure, and fatigue, these factors may all contribute to disease recurrence.