Does oral poliovirus attenuated live vaccine (human diploid cells) cause disability?

Oral poliovirus attenuated live vaccine (human diploid cells) is generally safe and used to prevent poliomyelitis (commonly known as infantile paralysis) in most cases. In very rare instances, this vaccine may cause adverse reactions, some of which can be severe, including limb paralysis, known as vaccine-associated paralytic poliomyelitis (VAPP). This condition typically occurs in individuals with immune deficiencies, those currently receiving immunosuppressive therapy, or those experiencing diarrhea. When the body is in an abnormal state, taking the oral poliovirus attenuated live vaccine may increase the risk of contracting the poliovirus and potentially lead to symptoms of limb paralysis. Therefore, before administering the vaccine, doctors usually assess the patient's health condition and vaccination history to ensure the safety of immunization.