What are the causes of oral leukoplakia?

The causes of oral leukoplakia mainly include the following points: 1. Local irritative factors: Smoking is the primary inducement for oral leukoplakia. Statistics show that 80% to 90% of patients with leukoplakia have a smoking habit, and the affected sites often correspond with the areas exposed to tobacco irritation. In addition, alcohol consumption, betel nut chewing, long-term residual tooth roots and crowns within the oral cavity, and poorly maintained or aged dental restorations can continuously irritate the oral mucosa, leading to the formation of leukoplakia. 2. Systemic factors: Deficiencies in vitamin B and folic acid, Candida albicans infection, syphilis, radiation exposure, xerostomia (dry mouth), and other conditions are closely associated with leukoplakia. Long-term psychological stress may also affect immune function and exacerbate the condition of oral leukoplakia. 3. Genetic factors: Oral leukoplakia may also be related to familial inheritance. Individuals with a genetic predisposition are more susceptible to developing this condition. To prevent and treat oral leukoplakia, it is necessary to avoid unhealthy lifestyle habits and irritative factors, maintain good oral hygiene, and pay attention to nutritional supplementation.