What causes thrombocytopenia (low platelet count)?

Jul 01, 2024 Source: Cainiu Health
Disease description:

My daughter often feels dizzy, sometimes experiences blackout vision during moments of stress, and recently almost fainted. A few days ago, I took her to the hospital for a checkup. The results showed that her platelet count is below the normal range. May I ask what are the causes of low platelet count?

Doctor's answer (1)
Dr. Liu Feng
The causes of thrombocytopenia are diverse and mainly include the following: 1. Disease factors: Infections, such as hepatitis virus infection, may cause thrombocytopenia. Immune-related diseases, such as primary immune thrombocytopenia, lead to excessive platelet destruction. Systemic diseases, such as systemic lupus erythematosus, aplastic anemia, and leukemia, can also trigger thrombocytopenia. 2. Genetic factors: Certain abnormal genes may cause impaired platelet production, reducing platelet formation. Hypersplenism, in which an enlarged spleen causes platelet sequestration within the spleen, decreases the number of platelets in the peripheral blood. Medications and surgical trauma: certain drugs and surgeries (e.g., heart valve surgery) may lead to increased platelet destruction or consumption. If symptoms of thrombocytopenia occur, prompt medical attention is necessary to identify the underlying cause and initiate appropriate treatment.