Does hemolysis affect biochemical test results?

Hemolysis can affect biochemical test results, primarily in the following aspects: 1. Liver function indicators: Hemolysis can cause liver damage, leading to elevated levels of transaminases and bilirubin, especially total bilirubin and indirect bilirubin. 2. Renal function indicators: Due to increased uric acid levels in the blood, hemolysis may cause creatinine values to be either higher or lower than normal during kidney function tests. 3. Other biochemical indicators: Hemolysis can also affect the concentrations of multiple enzymes in the serum, such as lactate dehydrogenase and aspartate aminotransferase, causing these indicators to rise. At the same time, the contents released from ruptured red blood cells may dilute other components in the serum, affecting the accuracy of test results. During biochemical testing, it is important to be aware of the possibility of hemolysis and take appropriate measures to prevent its occurrence.