What are the clinical symptoms of dyshidrotic eczema?

The clinical manifestations of dyshidrotic eczema are mainly characterized by the following: 1. **Vesicles**: These commonly occur on the palms, lateral aspects of the fingers and fingertips, soles, and sides of the toes. Vesicles are usually pinhead to rice-grain sized, round or hemispherical, slightly elevated above the skin surface, with clear or turbid vesicular fluid. 2. **Symmetrical distribution**: Vesicles often appear symmetrically, meaning both hands and feet may be affected simultaneously or nearly simultaneously. 3. **Associated symptoms**: Patients frequently experience significant itching or a burning sensation. Some may also have swelling and pain. In severe cases, vesicles may coalesce into larger bullae, potentially leading to nail dystrophy. 4. **Disease course**: Dyshidrotic eczema typically has a prolonged course and tends to recur, with symptoms often worsening during spring and summer. In summary, dyshidrotic eczema is clinically characterized by symmetrical small vesicles, associated symptoms such as itching and burning, and a chronic, recurrent course.