What are the clinical symptoms of uremia?
Disease description:
My father has had chronic nephritis for a long time, which has not been cured, and has now progressed to the stage of renal failure. His creatinine levels are also very high. I would like to ask about the clinical symptoms of uremia.
Doctor's answer (1)
Dr. Yang Ziqi
The clinical symptoms of uremia mainly include the following points:
1. **Gastrointestinal symptoms**: Such as nausea, vomiting, decreased appetite, gastrointestinal bleeding (hematemesis or black stools), and oral odor, which are relatively common early manifestations of uremia.
2. **Hematologic symptoms**: Anemia, bleeding tendencies (e.g., subcutaneous petechiae, ecchymosis, gum bleeding), and severe cases may develop massive gastrointestinal bleeding.
3. **Neurologic symptoms**: Early manifestations may include dizziness, headache, fatigue, and memory impairment; in later stages, symptoms of uremic encephalopathy such as restlessness, seizures, and coma may appear.
4. **Cardiovascular symptoms**: Such as hypertension, arrhythmia, and heart failure, which are common complications of uremia.
5. **Other symptoms**: Including edema, reduced urine output or anuria, skin itching, bone deformities, bone pain, and respiratory manifestations such as deep and prolonged breathing during acidosis.
The above symptoms may exist alone or concurrently and may worsen as the disease progresses.
