What to do about polycystic kidney disease genes
Disease description:
We are planning to get married, but during the pre-marital medical examination, I found out that my partner carries the gene for polycystic kidney disease. Therefore, we would like to know what we should do about the polycystic kidney gene?
Doctor's answer (1)
Dr. Yang Ziqi
Polycystic kidney disease requires a comprehensive approach to treatment:
1. **Gene therapy**: Introducing normal genes to replace abnormal ones, aiming to control the hereditary transmission of polycystic kidney disease; this is suitable for patients with clearly identified pathogenic gene mutations.
2. **Surgical treatment**: Procedures such as cyst decortication and cyst removal combined with vascular angioplasty can reduce damage to kidney function caused by cysts and slow disease progression.
3. **Pharmacological therapy**: The use of targeted drugs, such as angiotensin-converting enzyme inhibitors, to interfere with specific molecular pathways and control disease progression.
4. **Lifestyle interventions**: Improving dietary habits, reducing intake of high-salt and high-fat foods, and increasing regular physical activity to reduce the burden on the kidneys.
5. **Regular follow-up**: Regular monitoring of kidney function and ultrasound examinations to promptly detect disease progression and adjust treatment plans accordingly.
