Hereditary Bilateral Renal Cysts: What Is This Disease?
Disease description:
Recently, I have been feeling discomfort in the waist and abdominal area, with occasional sharp pains that are quite noticeable, and it has been a lingering, dull ache overall. After going to the hospital for a checkup, I found out it is hereditary bilateral renal cysts. May I ask, what kind of disease is this?
Doctor's answer (1)
Dr. Yang Ziqi
Hereditary bilateral renal cysts is a genetic disorder caused by gene mutations, with the main characteristics as follows:
1. Heredity: It is an autosomal dominant genetic disease. If either parent has the condition, the risk of offspring being affected is significantly increased.
2. Etiology: Due to gene mutations, especially mutations in the VHL gene, polycystic kidney disease may develop.
3. Clinical manifestations: Patients may experience symptoms such as flank pain, abdominal mass, hematuria, proteinuria, and renal function impairment. As the cysts enlarge, they may compress the kidneys and affect renal function.
4. Treatment: Treatment methods include cyst drainage, partial nephrectomy, cyst decortication, and gene therapy, with specific plans tailored according to individual patient conditions.
