What are the symptoms of duodenal ulcer?

The clinical manifestations of duodenal ulcers mainly include: 1. Upper abdominal pain: This is the most common symptom, presenting as dull, aching, distending, or burning pain in the epigastric or right upper quadrant. The pain is rhythmic and often occurs 1-3 hours after meals or at night, and can be relieved by eating. 2. Dyspepsia: Accompanied by symptoms such as heartburn, bloating, fullness, belching, and acid regurgitation, which affect the patient's digestive function. 3. Changes in appetite: Some patients may eat frequently to relieve pain, leading to weight gain; however, others may experience loss of appetite, nausea, and vomiting due to long-standing or severe ulcers. 4. Bleeding symptoms: When the ulcer penetrates the duodenal mucosa and involves blood vessels, it may cause melena or hematochezia. Severe cases can lead to hematemesis and anemia. 5. Other symptoms: Such as bowel problems including diarrhea or constipation, as well as nausea and vomiting in some patients.