Behçet's Disease Symptoms

Behçet's disease, also known as Behçet's syndrome, is a chronic, multisystem autoimmune disorder primarily characterized by vasculitis. Its clinical manifestations are diverse and mainly include: 1. Recurrent oral ulcers: Present in nearly 100% of patients, these ulcers are deep and painful, tend to recur frequently, and may affect multiple sites. 2. Genital ulcers: Approximately 75% of patients are affected, with involvement possible in both male and female genitalia, significantly impacting quality of life. 3. Ocular involvement: About 60%-70% of patients experience ocular damage, such as iritis and uveitis, which can lead to vision loss or even blindness in severe cases. 4. Dermatological symptoms: Around 80% of patients develop skin lesions, such as erythema nodosum and folliculitis, along with a positive pathergy (skin prick) reaction. 5. Joint involvement: About 50%-60% of patients have arthritis, typically presenting as monoarthritis or oligoarthritis, primarily causing pain. 6. Gastrointestinal tract involvement: Any part of the gastrointestinal tract can be affected, presenting with ulcers, bleeding, and potentially leading to acute abdomen in severe cases. 7. Neurological involvement: Manifestations such as meningitis and cerebral infarction can occur, resulting in symptoms like headache and altered consciousness, and are among the major causes of mortality. Behçet's disease presents with complex and varied symptoms, necessitating comprehensive diagnosis and prompt treatment to control disease progression.