What does it mean if alanine aminotransferase (ALT) levels are elevated?
Disease description:
During my physical examination, the doctor mentioned that my alanine aminotransferase (ALT) level is elevated. I would like to ask the doctor, what does it mean when alanine aminotransferase is high?
Doctor's answer (1)
Dr. Yang Ziqi
Elevated alanine aminotransferase (ALT) levels usually indicate liver damage. ALT is a common enzyme in the liver, and when liver cells are injured or destroyed, ALT is released into the bloodstream, causing elevated ALT levels in the blood. Common causes include:
1. Hepatitis: Viral infections such as hepatitis B or C, or non-viral hepatitis such as fatty liver disease or alcohol-related liver disease.
2. Excessive alcohol consumption: Long-term heavy drinking can cause liver damage.
3. Fatty liver disease: Associated with metabolic disorders such as obesity, diabetes, and high cholesterol.
4. Other diseases: Liver cirrhosis, liver cancer, bile duct obstruction, heart disease, and muscle injury may also affect ALT levels.
If elevated ALT levels are detected, timely medical evaluation is recommended.
