What happens if a couple's blood is incompatible?

Jul 16, 2024 Source: Cainiu Health
Disease description:

We want to have a child with our wife, but the doctor told us that our blood types are incompatible. What happens if a couple has incompatible blood types?

Doctor's answer (1)
Dr. Zhao Xiaodong
Blood incompatibility between couples usually refers to incompatible blood types of the two partners. This situation does not directly cause infertility or inability to conceive from a medical perspective, but it may increase the risk of hemolytic disease in the newborn. Specifically, if the mother has blood type O and the father has blood type A, B, or AB, or if the mother has Rh-negative blood (commonly known as "panda blood") and the father has Rh-positive blood, the fetus may experience a hemolytic reaction within the womb, with an increased risk especially during subsequent pregnancies. Hemolytic reactions may cause symptoms in the newborn such as jaundice and anemia, but in most cases, the symptoms are mild and recovery can be achieved through timely treatment. Therefore, couples should undergo blood type testing before conception and have regular hemolytic disease screenings during pregnancy to enable early detection and treatment. At the same time, maintaining healthy lifestyle habits and a balanced diet can also help reduce the risk of neonatal hemolysis.