Precautions for Taking Allopurinol

Jul 19, 2024 Source: Cainiu Health
Disease description:

I have always had gout, and it seems to have worsened this year before winter even began. I was prescribed some allopurinol. What should I be aware of when taking allopurinol?

Doctor's answer (1)
Dr. Yang Tiesheng
Precautions for taking allopurinol include: 1. Regular monitoring: During treatment, blood uric acid levels and 24-hour urinary uric acid levels should be regularly checked, along with complete blood count and liver and kidney function tests, to adjust the drug dosage. 2. Dietary control: Alcohol and tobacco should be avoided; limit consumption of high-purine foods (such as seafood, organ meats, etc.), maintain appropriate exercise, and ensure regular diet and作息 (作息 should be translated as "作息" here, but note that this word doesn't have a direct translation in English and might be better explained contextually as "daily routine" or "sleep-wake cycle"). 3. Drug interactions: Allopurinol should not be taken with iron supplements. When used in combination with uricosuric drugs, it may enhance therapeutic effects. 4. Adverse reaction monitoring: Nausea, vomiting, and other adverse reactions may occur after taking the medication. If severe, discontinue the drug immediately and seek medical attention. 5. Avoid discontinuation: Gout attacks may become more frequent during treatment with this medication. It is recommended not to stop taking the drug without consulting a physician; seek medical advice promptly and follow the doctor's instructions for medication use.