How long will insulin remain effective if not refrigerated?

Aug 13, 2024 Source: Cainiu Health
Disease description:

Recently, I forgot to refrigerate my insulin. How long will insulin remain effective if not refrigerated?

Doctor's answer (1)
Dr. Yang Ziqi

1. Unopened insulin: Under normal conditions, unopened insulin preparations can be stored at room temperature (not refrigerated) for approximately 30 months. However, exposure to high or low temperatures may accelerate its degradation, potentially causing it to lose activity within a week.

2. Opened insulin: Once opened, insulin preparations can be stored at room temperature (below 25°C) for about one month and should be protected from direct sunlight and high temperatures. Exposure to higher temperatures may alter its molecular structure, leading to reduced or complete loss of activity.

The exact expiration time is influenced by multiple factors, including the type of insulin, storage temperature, and duration. Therefore, insulin storage should follow professional guidelines. Additionally, always inspect the appearance and expiration date of insulin before use to ensure its safety and effectiveness. If you are unsure whether the insulin is still effective, consult a healthcare professional promptly.