Which category of antihypertensive drugs does the sustained-release nifedipine tablet belong to?

Amlodipine besylate sustained-release tablets belong to the class of antihypertensive medications known as calcium channel blockers. These drugs selectively inhibit the transmembrane influx of calcium ions into myocardial and smooth muscle cells and inhibit the release of calcium ions from intracellular stores, without altering plasma calcium ion concentrations.

The primary mechanism of action of amlodipine besylate sustained-release tablets is the inhibition of calcium influx, resulting in vascular smooth muscle relaxation, coronary artery dilation, increased coronary blood flow, enhanced myocardial tolerance to ischemia, and reduced peripheral vascular resistance, thereby lowering blood pressure.

Clinically, amlodipine besylate sustained-release tablets are primarily indicated for the treatment of hypertension, angina pectoris, and certain arrhythmias. They effectively control blood pressure levels without adversely affecting the patient's lipid or glucose levels, thereby contributing to the safety and effectiveness of treatment.

During use, it is necessary to follow the guidance and recommendations of a physician. Close monitoring of heart rate and blood pressure changes is also required in order to promptly detect and manage any abnormalities. Adverse effects such as tachycardia and lower limb edema should also be noted when taking this medication.