Which antihypertensive medication is best?

Aug 13, 2024 Source: Cainiu Health
Disease description:

I have a relative who has developed hypertension, but there are many antihypertensive medications available, and I don't know which one works best. May I ask, which antihypertensive medication is most effective?

Doctor's answer (1)
Dr. Tian Hongbo

In selecting antihypertensive medications, individual patient factors should be comprehensively considered, including the type of hypertension, complications, age, gender, concomitant medications, and personal preferences.

1. Calcium channel blockers: Such as nifedipine tablets, amlodipine besylate tablets, etc., which lower blood pressure by blocking calcium ions from entering cells and thereby relaxing vascular smooth muscle. These are suitable for elderly patients with hypertension or those with isolated systolic hypertension.

2. Diuretics: Suitable for mild to moderate hypertension, especially isolated systolic hypertension in the elderly and patients with heart failure.

3. Angiotensin-converting enzyme inhibitors (ACEI): Such as captopril tablets, enalapril maleate tablets, etc., which lower blood pressure by inhibiting the production of angiotensin II and dilating blood vessels. These are most suitable for patients with target organ damage such as the heart and kidneys.

4. Beta-blockers: Suitable for angina pectoris, post-myocardial infarction, tachyarrhythmia, chronic heart failure, etc.

Patients should follow medical advice and choose the antihypertensive medication most suitable for themselves.