Cause of Parkinson's Disease
Disease description:
My grandfather is getting older, and we don't know exactly when it started, but he has been experiencing hand tremors constantly. After a hospital examination, he was diagnosed with Parkinson's disease. However, he seemed perfectly fine before. I would like to ask what causes Parkinson's disease?
Doctor's answer (1)
Dr. Lv Zhiqin
Etiology of Parkinson's disease:
1. Genetic factors: Genetic factors account for a certain proportion of Parkinson's disease cases. About 10% of patients have a family history, indicating that certain genetic variations may be associated with the development of Parkinson's disease.
2. Environmental factors: Long-term exposure to toxic chemicals, such as pesticides and heavy metals, may increase the risk of developing Parkinson's disease. In addition, air pollution and unhealthy lifestyle habits may also have some influence on the onset of the disease.
3. Age factors: Parkinson's disease primarily occurs in middle-aged and elderly individuals. As age increases, the prevalence of the disease rises gradually. This may be related to the degenerative changes in brain neurons.
4. Neurodegeneration associated with aging: With increasing age, dopaminergic neurons in the substantia nigra undergo degenerative changes, and the number of dopamine neurons progressively decreases, which may be one of the key factors in the pathogenesis of Parkinson's disease.
