How to treat kidney inflammation with one plus sign of protein in urine?
Disease description:
During this period, I have constantly felt a dull pain in my kidneys. When I went to the hospital for a blood test, I found that my urine protein tested positive with one plus sign. The doctor diagnosed it as Henoch-Schönlein purpura nephritis. What should I do?
Doctor's answer (1)
Dr. Yang Guang
IgA vasculitis (Henoch-Schönlein purpura) nephritis is a complication of Henoch-Schönlein purpura, mainly manifested as skin purpura, joint pain, abdominal pain, and kidney damage. Treatment approaches for patients with one plus sign of urinary protein:
1. Lifestyle modification: Improving living habits through healthy diet and regular exercise can help reduce urinary protein. This method is suitable for patients with mild urinary protein and can serve as an adjunctive treatment.
2. Pharmacological therapy: Antihistamines and nonsteroidal anti-inflammatory drugs can be used to relieve symptoms such as skin purpura and joint pain. Glucocorticoids may be used in severe cases of Henoch-Schönlein purpura nephritis, especially in patients with significant proteinuria or renal insufficiency, to suppress the immune response and reduce inflammation.
3. Immunosuppressive agents: If glucocorticoids are not effective, immunosuppressive agents such as cyclophosphamide or mycophenolate mofetil may be used in combination to more effectively control the immune response.
4. Regular monitoring: Patients need close monitoring of disease progression and regular follow-up tests including urinalysis and renal function assessment.
