Is it advisable for menopausal women with coronary heart disease to take Deanxit long-term?
I am a 43-year-old woman entering menopause, and I would like to take the medication Daili (Tibolone) to regulate my mood. However, I have coronary heart disease. May I ask if it is safe for me to take this medication long-term?
Menopausal patients with coronary heart disease are not recommended to take Deanxit long-term.
Deanxit is primarily used to treat mild to moderate depression and anxiety, as well as depression associated with menopause. For menopausal patients with concomitant coronary heart disease, medication selection should be based on a comprehensive assessment of the patient's cardiovascular condition, mental status, and potential drug interactions.
Long-term use of Deanxit may have certain effects on patients with coronary heart disease, as the drug may influence cardiac electrophysiological activity. When considering long-term administration, changes in the patient's electrocardiogram (ECG) must be closely monitored to avoid the risk of potential arrhythmias. Although adverse reactions are minimal at recommended doses, long-term use may increase the risk of extrapyramidal reactions, such as upward rolling of the eyes, torticollis, and retrocollis. Additionally, long-term administration of Deanxit may lead to dependency, making discontinuation difficult. Deanxit may also interact with other medications used to treat coronary heart disease, such as antiplatelet drugs and beta-blockers, which requires careful evaluation by a physician.