What causes elevated gamma-glutamyl transferase (GGT) and frequent fever?
Disease description:
Recently, I've had a bit of a cold with persistent fever, and after going to the hospital for a physical examination, I found that my gamma-glutamyl transferase (GGT) level was elevated. I would like to ask, what are the common causes of elevated GGT levels accompanied by frequent fever?
Doctor's answer (1)
Dr. Shen Yonghua
Gamma-glutamyl transferase (GGT) is an enzyme widely present in the liver, kidneys, and pancreas. Elevated levels of GGT in the blood typically indicate possible damage or disease in these organs. Common conditions include hepatitis, fatty liver disease, bile duct obstruction, and pancreatitis. If elevated GGT is accompanied by frequent fever, it may suggest the presence of infectious or inflammatory diseases, such as viral hepatitis, cholecystitis, cholangitis, or pancreatitis. Excessive accumulation of fat within liver cells can lead to abnormal liver function, which in turn may cause elevated GGT levels and fever. Poor emotional well-being, high stress levels, and overwork may also lead to abnormal liver function and elevated GGT. Additionally, long-term use of certain medications, such as phenobarbital and phenytoin sodium, may affect the liver and result in elevated GGT levels. In daily life, chronic alcohol consumption and autoimmune diseases may also lead to elevated GGT levels and fever.
It is recommended that patients undergo a comprehensive physical examination, including biochemical blood tests, abdominal ultrasound, or CT scans, to determine the underlying cause and receive appropriate treatment.
