Symptoms of decompensated cirrhosis following hepatitis B

Sep 25, 2024 Source: Cainiu Health
Disease description:

My grandfather was recently diagnosed with hepatitis B. Recently, he developed ascites, and the doctor at the hospital indicated it is decompensated cirrhosis following hepatitis B. I would like to learn more about the symptoms associated with this condition.

Doctor's answer (1)
Dr. Shen Yonghua

Decompensated cirrhosis due to hepatitis B is an advanced stage of cirrhosis in which the patient's liver function has been severely impaired, accompanied by multiple complications. The main clinical manifestations at this stage include the following:

1. Ascites: Due to portal hypertension and hypoalbuminemia, patients develop marked abdominal distension, which may be accompanied by abdominal fullness and shortness of breath.

2. Jaundice: Yellowing of the skin and sclera, dark-colored urine resembling tea, and pale or clay-colored stools indicate impaired bilirubin metabolism.

3. Esophageal varices: These may cause hematemesis or melena, resulting from increased pressure in the esophageal veins due to portal hypertension, leading to rupture and bleeding.

4. Hepatic encephalopathy: Manifested as changes in personality, abnormal behavior, confusion, or even coma, this results from the accumulation of ammonia and other toxins in the body affecting brain function.

5. Loss of appetite and weight loss: Patients frequently experience anorexia and reduced food intake, leading to significant weight loss.

6. Nausea and vomiting: Impaired liver function affects digestion and absorption in the gastrointestinal tract, potentially causing symptoms such as nausea and vomiting.