Patients with hepatitis B who want to switch medications are advised by doctors to follow the prescribed treatment regimen.

Nov 25, 2024 Source: Cainiu Health
Disease description:

I am a hepatitis B patient who has been taking the current medication for some time and would like to switch medications, but my doctor advises to follow the prescribed treatment. Why can't I change medications?

Doctor's answer (1)
Dr. Gao Jun

Most medications for hepatitis B work in multiple areas, such as suppressing hepatitis B virus replication and controlling liver inflammation. Doctors may not recommend switching medications because the current treatment may have already achieved a relatively stable condition. Changing medications arbitrarily might disrupt this balance. Different hepatitis B drugs have varying mechanisms of action, and switching medications could lead to suboptimal therapeutic effects, viral rebound, or increased adverse reactions. Moreover, the hepatitis B virus has a tendency to mutate, and the newly introduced medication may not be effective against the mutated viral strains.

It is recommended to communicate fully with your doctor to understand the specific reasons for not recommending a medication change. If you still have concerns about switching medications, you may request your doctor to conduct a more detailed evaluation of your current condition, including viral load, liver function indicators, and liver imaging studies, to determine whether changing medications is truly necessary.