Causes of bilateral lower limb edema

Nov 28, 2024 Source: Cainiu Health
Disease description:

Recently, I noticed significant swelling in both of my lower limbs. When pressed with my finger, an indentation remains for quite some time before recovering. Additionally, my legs feel heavy and walking has become somewhat difficult. What could be causing this?

Doctor's answer (1)
Dr. Chen Jian

Swelling of both lower limbs, medically termed "lower limb edema," is a common symptom that can be caused by various factors. Below are some potential causes:

1. Heart diseases: Heart failure is a common cause of lower limb edema. When the heart is unable to pump blood effectively, blood can accumulate in the lower limbs, causing fluid to leak into surrounding tissues and form edema.

2. Kidney diseases: Conditions such as renal failure, nephritis, and nephrotic syndrome can also lead to bilateral lower limb edema. These conditions are usually associated with abnormal hemodynamic changes in the circulatory system.

3. Liver problems: Cirrhosis of the liver and hypoalbuminemia caused by malnutrition are also common causes of bilateral lower limb edema.

4. Venous problems: Venous system disorders such as deep vein thrombosis, varicose veins, or chronic venous insufficiency can impede blood return, increase pressure in the lower limbs, and lead to edema.

5. Lymphatic system disorders: Blockage of lymphatic vessels or damage to lymph nodes can obstruct lymphatic drainage, leading to localized or generalized edema, especially limb swelling.

6. Medication side effects: Certain medications such as antihypertensive drugs, nonsteroidal anti-inflammatory drugs (NSAIDs), and hormonal medications may cause lower limb edema as a side effect.

7. Physiological factors: Prolonged standing or sitting, excessive physical activity, and exposure to high temperatures may temporarily cause lower limb edema.