
What is the prognosis for ankylosing spondylitis?
I suffer from ankylosing spondylitis and frequently experience lower back pain, with limited range of motion. I am currently undergoing active treatment, but I still worry about my future condition. What is the prognosis for ankylosing spondylitis? Will I be able to live a normal life after treatment?

Ankylosing spondylitis is a chronic inflammatory disease that primarily affects the spine and sacroiliac joints, causing pain, stiffness, and, in some cases, fusion of the spine. The prognosis is influenced by multiple factors, including disease severity, timing of diagnosis and treatment, the patient's lifestyle, and genetic factors.
1. Disease Activity and Functional Status
Early diagnosis and timely treatment can improve the prognosis. Modern treatment approaches, such as biologic agents, can effectively control disease activity, reduce joint damage, and maintain or improve the patient's functional status. However, if the disease progresses to an advanced stage, structural damage to the spine and other joints may become irreversible, leading to persistent pain and functional limitations.
2. Complications
Patients with ankylosing spondylitis are at risk for complications such as cardiovascular disease, eye inflammation, lung disease, and gastrointestinal issues.
Although genetic factors play a significant role in the development of ankylosing spondylitis, environmental factors such as infections and lifestyle can also influence disease progression. It is important to avoid known triggers, such as tobacco smoke, which can help alleviate symptoms.
Therefore, patients should actively pursue treatment and engage in appropriate exercise and care to achieve the best possible prognosis.