How to treat elevated alanine aminotransferase (ALT)

Alanine aminotransferase (ALT) is an enzyme primarily found within liver cells. When liver cells are damaged, ALT is released into the bloodstream, causing elevated levels of ALT in the blood.

It is recommended to identify and avoid causative factors, such as abstaining from alcohol consumption and discontinuing medications that may cause liver cell toxicity. For conditions such as viral hepatitis and cirrhosis, appropriate treatments should be undertaken, including antiviral therapy and liver-protective measures. If elevated ALT levels are caused by viral hepatitis, antiviral treatment may be required; if caused by alcohol or medications, alcohol consumption should be stopped or the relevant medications discontinued; if due to fatty liver disease, weight reduction through dietary control and increased physical activity is recommended to improve metabolic status. Under a physician's guidance, enzyme-lowering medications such as glycyrrhizinic acid preparations and isoglycyrrhizic acid may be taken, as these drugs help reduce alanine aminotransferase levels. Lifestyle modifications, including maintaining good sleep habits, adequate rest, and avoiding staying up late and overexertion are advised. Emotional regulation to maintain a happy mood and avoid anger or depression is also important. Engaging in appropriate physical exercise can enhance immune function, although excessive fatigue should be avoided. Smoking and alcohol consumption should be avoided to prevent further damage to the liver.