How is "Big Three Yang" treated?

Mar 31, 2025 Source: Cainiu Health
Disease description:

I was found to have "big three positives" during a physical examination. I feel anxious and worried about the progression of the disease. What treatment options are available for someone in my situation, and can the disease progression be controlled?

Doctor's answer (1)
Dr. Gao Jun

"Big Three Positive" is a manifestation of chronic hepatitis B, referring to the simultaneous presence of hepatitis B surface antigen, hepatitis B e-antigen, and hepatitis B core antibody IgM in the patient's blood. It can generally be treated through dietary adjustments, improved lifestyle habits, and medication.

Maintain a balanced diet and avoid spicy, raw, cold, or greasy foods. Consuming more high-quality proteins, vitamins, and other nutrients helps repair liver cells. Abstaining from alcohol, avoiding excessive fatigue, maintaining a healthy diet, and going to bed early and waking up early help reduce the burden on the liver and promote recovery.

Currently, nucleoside analogs such as entecavir, tenofovir, or interferon are mainly used for treatment. These medications can effectively inhibit viral replication but require long-term use and dosage adjustments under a doctor's guidance. Liver-protecting medications are used to improve liver function and reduce liver cell damage.

Patients with "Big Three Positive" hepatitis B should regularly monitor indicators such as liver function and the level of hepatitis B virus replication and adjust their treatment plans timely according to medical advice.