Is niacinamide harmful to the body?

May 16, 2023 Source: Cainiu Health
Dr. Yang Shuwen
Introduction
Under normal use, niacinamide is not harmful to the body and can help brighten skin tone and improve rough, dull skin. However, in individuals allergic to the drug, it may cause symptoms such as skin itching, redness, swelling, and pain, and may trigger respiratory weakness, breathing spasms, and excessive sweating. In severe cases, it could lead to limb paralysis and even result in death.

Under normal use, niacinamide is not harmful to the body; however, long-term use may cause harm. The detailed analysis is as follows:

1. Not Harmful

Niacinamide is a component of coenzyme I and coenzyme II, and participates in metabolic processes in the body, including carbohydrate breakdown, lipid metabolism, and oxidative reactions involved in tissue respiration. However, it does not have vasodilatory effects. Topical application of niacinamide can brighten skin tone. For individuals with rough or dull skin, skin condition can improve significantly after using it.

2. Harmful

If a patient is allergic to the drug, its use may trigger adverse reactions such as skin itching, redness, pain, rashes, nausea, and vomiting. Long-term use may lead to symptoms like weakened breathing, respiratory spasms, and excessive sweating. Prolonged use could even result in paralysis.

In summary, niacinamide should only be used under the guidance of a physician. Self-medication is not recommended. If any adverse reactions occur after use, prompt medical attention is necessary.


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