What are the potential harms of long-term use of glycerin suppositories on the body?

Long-term use of Glycerin Suppositories may lead to risks such as drug dependence, habitual constipation, perianal skin damage, intestinal dysfunction, abrasions, and infection. If concerned, it is recommended to seek medical advice in advance. Detailed explanations are as follows:

1. Drug Dependence: Prolonged use of Glycerin Suppositories may suppress the defecation reflex, reducing the rectum's sensitivity to fecal matter and weakening the body's natural ability to defecate. The intestines may develop tolerance to the medication's stimulation, ultimately resulting in dependence on the suppository for bowel movements.

2. Habitual Constipation: The glycerin in Glycerin Suppositories has strong water-absorbing properties. Frequent use may cause intestinal dryness. A lack of moisture in the intestinal walls can further worsen constipation symptoms, leading to habitual constipation.

3. Perianal Skin Damage: Frequent use of Glycerin Suppositories can continuously irritate the skin around the anus, potentially causing itching, pain, bleeding, or rashes.

4. Intestinal Dysfunction: Long-term excessive use of Glycerin Suppositories can continuously stimulate the intestines, possibly causing overactive bowel movements and resulting in discomfort such as abdominal pain and diarrhea. Over time, it may also cause gastrointestinal nerve dysfunction, further affecting digestive function.

5. Risk of Abrasions and Infections: The plastic tip of the suppository is relatively hard, and frequent insertion may cause abrasions in the anal area. Wounds in the excretory region are more prone to infection and may be difficult to heal.

Patients suffering from chronic constipation should actively adjust their diet, increase intake of fiber-rich foods such as celery and whole grains, and engage in more physical activity to promote gastrointestinal motility.