Clinical and Pathological Staging of Appendicitis and Timing of Surgical Intervention
First, acute simple appendicitis can be effectively managed with conservative antimicrobial therapy.
Second, acute suppurative appendicitis typically evolves from acute simple appendicitis. It is characterized by thin purulent fluid in the peritoneal cavity surrounding the appendix, leading to localized peritonitis. Clinical signs and symptoms are more severe, and surgical intervention is required in most cases.
Third, gangrenous and perforated appendicitis is a severe form of appendicitis. Perforation most commonly occurs at the base or tip of the appendix and may precipitate acute diffuse peritonitis, necessitating emergency surgery.
Periappendiceal abscess, acute suppurative appendicitis, suppuration, and gangrenous perforation may trigger migration of the greater omentum to the right lower abdomen, where it envelops the appendix, resulting in adhesions and formation of a palpable mass or periappendiceal abscess.