What causes pain or burning in the urethra during urination?
In daily life, urethral pain during urination is commonly caused by urinary tract infections or urinary stones. If due to a urinary tract infection, symptoms typically include genital itching, redness, swelling, and painful urination (dysuria); treatment often involves antibiotic therapy. If the pain results from kidney or bladder stones, additional symptoms may include urinary hesitancy, dysuria, and crystalluria. Increasing fluid intake to promote diuresis or using medications to dissolve stones may be recommended.
What Causes Urethral Pain During Urination?
1. Urinary Stones
Urinary stones can cause urethral pain during urination—particularly when stones are actively moving through the urinary tract. As stones pass from the kidneys into the bladder and then through the urethra, they irritate the urethral mucosa, resulting in sharp, stabbing pain. This pain is frequently accompanied by hematuria (blood in the urine), and the condition may be relatively severe. Initial diagnosis is typically made via renal and bladder ultrasound and urinalysis.

2. Prostatitis
Prostatitis may also cause urethral pain during urination, as dysuria is a hallmark symptom of this condition. Additional associated symptoms may include urinary frequency, urgency, urinary stream splitting (urinary bifurcation), weak urinary stream, and lower abdominal heaviness or discomfort. Notably, dysuria caused by prostatitis differs clinically from that caused by urinary stones, making differentiation generally straightforward. Diagnosis typically relies on urinalysis, urinary tract ultrasound, and prostate fluid analysis.
3. Other Conditions
Other potential causes of dysuria include urethritis, benign prostatic hyperplasia (BPH), cystitis, bladder tuberculosis, pyelonephritis, and even urological malignancies. In such cases, identifying the underlying etiology is essential for targeted treatment, and most conditions respond well to appropriate therapy. However, these diagnoses are relatively uncommon in clinical practice—especially urethritis in males, which is rare compared with prostatitis and urinary stones. Similarly, dysuria attributable to BPH, cystitis, or tuberculosis tends to be atypical and less frequently encountered.
The above provides an overview of potential causes of urethral pain during urination. We hope this information is helpful to you.