What is immunoglobulin G?
Apr 20, 2022
Source: Cainiu Health
Dr. Li Man
Introduction
Immunoglobulin G (IgG) is the predominant immunoglobulin in serum and plays a critical role in human immunity. It can inhibit various bacteria and viruses and exerts neutralizing effects, thereby providing defense and protective functions for the body. Elevated serum IgG levels are observed in conditions such as systemic lupus erythematosus, atrophic portal cirrhosis, chronic active hepatitis, and rheumatoid arthritis.
With the accelerating pace of modern life, some individuals often lack regular physical exercise, leading to a decline in immune function. But what exactly is immunoglobulin G?
What is Immunoglobulin G?
Immunoglobulin G (IgG) is the predominant immunoglobulin in human serum and plays a vital role in the body. Immunoglobulins serve multiple functions: they inhibit numerous bacteria and viruses, neutralize toxins and pathogens, and provide critical defense and protective functions for the host. Notably, IgG is the only antibody class capable of crossing the placenta, thereby conferring passive immunity and helping protect the fetus against infections.
Elevated serum IgG levels are observed in conditions such as systemic lupus erythematosus, atrophic portal sclerosis, chronic active hepatitis, rheumatoid arthritis, subacute bacterial endocarditis, IgG myeloma, certain infectious diseases, and IgG-type monoclonal gammopathy. IgG constitutes approximately 75% of total immunoglobulins in serum. Upon antigen stimulation, B lymphocytes differentiate into plasma cells that produce antibodies—immunoglobulins—capable of specifically binding to their corresponding antigens.
In daily life, engaging regularly in appropriate physical exercise can significantly enhance one’s resistance to disease. Additionally, maintaining a balanced diet rich in high-quality protein is highly recommended. We hope this information proves helpful to you.
