How to distinguish eczema from cradle cap

Apr 26, 2022 Source: Cainiu Health
Dr. Liu Wan
Introduction
Newborn babies have a greasy layer on their skin surface, composed of sebum and secretions from epidermal cells, known as “vernix caseosa.” Some infants develop dry, flaky scales on the scalp—resembling dandruff—that may progress to become thick, oily, scaly, and crusty patches, sometimes yellow or brown in color. This common condition is called “cradle cap,” also known as “seborrheic dermatitis of the scalp.”

Eczema is a common allergic, inflammatory skin disorder characterized by polymorphic rashes, symmetrical distribution, intense pruritus (itching), recurrent episodes, and a tendency to become chronic. So, how can one differentiate eczema from cradle cap?

How to Differentiate Eczema from Cradle Cap

Newborns naturally possess a protective oily layer on their skin, composed of sebum secreted by the skin and epidermal cells—this is known as “vernix caseosa.” In some infants, dry, flaky scales resembling dandruff appear on the scalp; over time, these may thicken and become greasy, forming scaly or crusty patches that range in color from yellow to brown. This common condition is termed “cradle cap” (or infantile seborrheic dermatitis). It results from overactive sebaceous glands in the infant’s scalp, where accumulated sebum—when not promptly removed—mixes with debris and forms thick, adherent crusts. Cradle cap typically develops when an infant’s scalp is not washed regularly, allowing sebum and environmental dust to accumulate over time.

Eczema and cradle cap present with distinct clinical features. In eczema, the skin exhibits red, inflamed papules or plaques; it may manifest as either dry (xerotic) or wet (exudative) eczema. Pruritus is prominent, often accompanied by a distinct stinging or burning sensation. In contrast, cradle cap primarily presents as thick, greasy, yellowish-brown scales or crusts on the scalp. Although mild itching may occur, it is generally less intense than in eczema. The scalp appears excessively oily due to hyperactive sebaceous glands; scratching may cause skin fissures and even serous exudation, which subsequently dries and forms crusts.

For definitive diagnosis, a skin biopsy with histopathological examination may be performed. We hope this information is helpful!

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