Normal Protein Values
May 22, 2022
Source: Cainiu Health
Dr. Li Man
Introduction
In medicine, hypoalbuminemia generally refers to serum albumin levels below 30 g/L, which may result from malnutrition, inadequate dietary intake, impaired liver function, or even reduced synthesis. Normal albumin values vary with age: in newborns, the reference range is 28–44 g/L; in adolescents aged 14–18 years, it is 38–54 g/L; and in adults, it is 35–50 g/L.
Proteins are the material basis of life—complex organic macromolecules and fundamental organic components of cells. All cells in the human body, as well as all vital structures, contain proteins. So what are the normal reference ranges for serum proteins?
Normal Reference Ranges for Serum Proteins
In clinical medicine, hypoalbuminemia generally refers to serum albumin levels below 30 g/L. This condition may result from malnutrition, inadequate dietary intake, impaired liver function, or insufficient albumin synthesis. Normal albumin levels vary with age: - Newborns: 28–44 g/L - Adolescents (14–18 years): 38–54 g/L - Adults: 35–50 g/L - Elderly (≥60 years): 34–48 g/L Serum globulin—the other major plasma protein fraction—typically ranges from 20–30 g/L.
Albumin levels below 40 g/L indicate decreased albumin; levels below 30 g/L signify a marked reduction, often necessitating intravenous albumin administration to maintain nutritional balance and preserve oncotic pressure across capillary membranes (i.e., tissue and fluid homeostasis). Markedly low albumin is commonly observed in patients with catabolic disorders, nephrotic syndrome, malnutrition, or those unable to eat normally. In addition to albumin infusion, dietary supplementation remains critically important.
Proteins constitute approximately 18% of total human body mass. Standard biochemical reference ranges are as follows: - Serum albumin: 40–50 g/L - Serum globulin: 20–30 g/L - Total serum protein: 60–80 g/L Dietary sources rich in high-quality protein—including milk, eggs, and seafood—can help meet daily protein requirements. We hope this information is helpful!
