Normal Progesterone Levels During Pregnancy Reference Chart
May 23, 2022
Source: Cainiu Health
Dr. Lv Aiming
Introduction
Progesterone, also known as gestagen or corpus luteum hormone, is a common progestogen secreted by the ovaries. During pregnancy, progesterone levels also change, typically increasing with advancing gestational age. During the follicular phase, progesterone levels range from 0.6–1.9 nmol/L; after ovulation, levels rise significantly, generally reaching 20.7–102.4 nmol/L. At 4–6 weeks of gestation, progesterone levels range from 19.4–95.3 nmol/L.
In daily life, many women experiencing their first pregnancy are unfamiliar with fundamental reproductive health knowledge. To better assess maternal and fetal health, it is essential to confirm that certain biomarker values fall within normal ranges. What, then, are the normal reference values for progesterone during pregnancy?
Normal Progesterone Reference Values During Pregnancy
Progesterone—also known as gestagen or corpus luteum hormone—is a steroid hormone primarily secreted by the ovaries. Following conception, progesterone levels undergo significant changes, generally increasing progressively with advancing gestational age. During the follicular phase, normal progesterone levels range from 0.6–1.9 nmol/L; after ovulation, they rise substantially, typically reaching 20.7–102.4 nmol/L. During weeks 4–6 of gestation, progesterone levels range from 19.4–95.3 nmol/L; at weeks 6–7, levels are approximately 76.4–23.7 nmol/L; at week 8, 89.2–24.6 nmol/L; at weeks 9–12, 118.6–40.6 nmol/L; at weeks 13–16, 98.3–185.7 nmol/L; and at weeks 17–20, 153.8–241.2 nmol/L.
Progesterone levels are closely associated with early pregnancy outcomes. Women experiencing embryonic demise or ectopic pregnancy typically exhibit significantly lower progesterone levels compared with those presenting signs of threatened miscarriage or those with uncomplicated early pregnancies. A serum progesterone level of 15–25 ng/mL generally indicates an intrauterine pregnancy but carries an elevated risk of early threatened miscarriage.
During pregnancy, it is advisable to minimize intake of spicy, heavily seasoned, or otherwise irritating foods, and instead emphasize fresh fruits and vegetables. Maintain regular work-rest schedules, avoid excessive physical exertion, ensure adequate rest for optimal fetal development, and attend all scheduled prenatal check-ups. We hope this information proves helpful!
