What is the inheritance pattern of Hemophilia C?
Disease description:
Nowadays, an increasing number of people are suffering from hemophilia. I would like to ask, what is the inheritance pattern of hemophilia C?
First, hemophilia is a group of inherited bleeding disorders characterized by impaired blood coagulation. The common feature is defective generation of active thromboplastin, resulting in prolonged clotting time and a lifelong tendency to bleed following minor injuries. Severely affected individuals may also experience spontaneous bleeding without obvious trauma. It is a congenital deficiency of clotting factors. Congenital factor VIII deficiency is a classic example of X-linked recessive inheritance, transmitted by females and manifested in males.