Can a skin biopsy detect psoriasis?

Skin biopsy is usually able to detect psoriasis. Psoriasis is a chronic inflammatory skin disease whose pathological changes mainly involve the epidermis. During a skin biopsy, the doctor will extract a tissue sample from the affected area and examine it in detail under a microscope to identify specific cellular or structural abnormalities, thereby confirming the diagnosis of psoriasis. This method is highly accurate and reliable for diagnosing psoriasis. However, whether or not to perform a skin biopsy should be determined based on the patient's specific condition and the extent of skin lesions. For patients with mild skin involvement, a biopsy may not be necessary, as other diagnostic methods such as physical examination, X-ray examination, and blood tests may also provide useful information. Nevertheless, once psoriasis is diagnosed, timely treatment and appropriate disease management are crucial.