Perioral Dermatitis Treatment
Rash may appear on the upper lip, nose, forehead, and other areas. Its exact cause remains unclear but is thought to be associated with external irritants—such as fluoridated toothpaste, cosmetics, lipstick, alcohol, or chewing gum. Perioral dermatitis can manifest as erythema, papules, vesicles, pruritus, and a burning sensation; prompt treatment is therefore essential. So, how is perioral dermatitis treated?
Treatment of Perioral Dermatitis
Patients with perioral dermatitis should discontinue use of fluoridated toothpaste to avoid further external irritation. Antihistamines—including eszopiclone hydrochloride tablets, cetirizine hydrochloride tablets, and loratadine tablets—may be administered. Under medical supervision, adjunctive therapy may include compound vitamin B tablets, compound glycyrrhizin tablets, and Runzao Zhiyang capsules. Given the facial skin’s delicacy, topical corticosteroid ointments should be avoided whenever possible. Alternative treatments—such as zinc borate oxide–borneol cream, tacrolimus ointment, and Chushi Zhiyang ointment—can help alleviate pruritus and burning sensations. Phototherapy using red or blue light may also be considered.

During the acute phase of perioral dermatitis, patients may develop erythema, edema, papules, and vesicles. Alkaline soaps can irritate the skin and exacerbate inflammation; therefore, gentle cleansers—or even plain water—should be used for facial cleansing. Perioral dermatitis often follows a protracted course and tends to recur; thus, patients must maintain patience throughout treatment.

In daily life, patients should adhere to a balanced diet, avoiding spicy or irritating foods, overeating, and staying up late. We hope this information proves helpful.