What antihypertensive medications should be used for renal hypertension?
Renal hypertension requires antihypertensive drugs that have protective effects on the kidneys, such as commonly used ACE inhibitors or ARBs, as well as diuretics and beta-blockers.
1. ACE inhibitors or ARBs: The choice depends on the specific type of renal hypertension. For common types such as hypertensive nephropathy, ACE inhibitors or ARBs are recommended—for example, compound enalapril maleate tablets or losartan potassium tablets. For renovascular hypertension or unilateral renal artery stenosis, calcium channel blockers are preferred for blood pressure control, such as nifedipine sustained-release tablets.
2. Diuretics: These work by promoting the excretion of excess fluid and potassium ions from the body through urine, thereby lowering blood pressure and reducing the kidney's workload. A commonly used example is intravenous furosemide. However, diuretics are not recommended in cases of high renin states.
3. Beta-blockers: These lower blood pressure by blocking catecholamines from binding to beta-adrenergic receptors, thus improving myocardial contractility and alleviating symptoms. Commonly used medications include bisoprolol fumarate capsules and metoprolol tartrate tablets, which generally have relatively few adverse effects on the kidneys.
Since different medications vary in their mechanisms and administration methods, patients requiring drug treatment for renal hypertension should be managed under the guidance of a qualified physician.