How many years does it usually take for atypical squamous cells to become cancerous?

Mar 25, 2023 Source: Cainiu Health

Dr. Yang Ziqi

Introduction

Atypical squamous refers to atypical squamous cells. The time it takes for atypical squamous cells to progress to cancer varies from several decades to a few months, depending on the risk level and pathological severity of the cancer. If atypical squamous cells are found, HPV testing can be used for confirmation. If only atypical squamous cells are present and all other tests are negative, further management may depend on clinical evaluation.

Atypical squamous refers to atypical squamous cells. Typically, there is no clear timeline for the potential malignant transformation of atypical squamous cells—some atypical squamous cells may never become cancerous, while others may progress to cancer. The progression period can range from several months to decades. Patients are advised to promptly visit a hospital and follow medical guidance for treatment. The analysis is as follows:

Grade 1 atypical squamous cell changes are benign and low-risk lesions that require only treatment of the underlying condition. In such cases, the risk of malignant transformation is relatively low, and the time to possible canceration may be long. Grade 2 atypical squamous cell changes are considered moderate-risk lesions. In addition to treating the primary disease, regular follow-up examinations are necessary to prevent canceration. At this stage, the risk of cancer increases but can still be reduced through timely intervention.

Grade 3 atypical squamous cell changes are high-risk precancerous lesions that generally require surgical treatment along with regular follow-up exams. In these cases, the risk of canceration is significantly higher, and the transformation may occur within months or a few years.

If atypical squamous cells are detected, HPV testing can help confirm the diagnosis. If only atypical squamous cells are present and all other tests are negative, special treatment is usually not required—regular hospital check-ups are sufficient. However, if HPV testing results are abnormal, further evaluation under a doctor's guidance—including colposcopy and pathological biopsy—is needed to determine whether cancerous or precancerous changes have occurred. If precancerous lesions are confirmed, surgical treatment should be administered under medical supervision.

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