What are the consequences of rhabdomyolysis?
Mar 25, 2023
Source: Cainiu Health
Dr. Lin Yunfei
Introduction
Rhabdomyolysis refers to a syndrome of skeletal muscle breakdown, which can lead to complications such as disseminated intravascular coagulation (DIC), the triad of symptoms, and compartment syndrome. The release of intracellular muscle contents into the bloodstream causes disseminated intravascular coagulation. The triad includes symptoms such as pain in the neck, shoulders, and back, muscle weakness, and reduced urine output. Increased pressure within the muscle fascia compresses arteries and impairs blood supply, resulting in compartment syndrome.
Rhabdomyolysis generally refers to rhabdomyolysis syndrome, which typically leads to complications such as disseminated intravascular coagulation, the classic triad of symptoms, and compartment syndrome. Specific analyses are as follows:
1. Disseminated Intravascular Coagulation (DIC)
When large amounts of substances from damaged muscle cells are released into the bloodstream, numerous microthrombi may form, leading to continuous consumption of clotting factors and resulting in disseminated intravascular coagulation.
2. The Classic Triad
Patients may experience muscle pain in the neck, shoulders, back, thighs, or lower back, accompanied by muscle swelling and tenderness. They may also develop muscle weakness, significantly darkened urine, and reduced urine output.
3. Compartment Syndrome
After muscle necrosis and edema, large volumes of fluid accumulate locally, increasing pressure within the muscle fascia compartments. This elevated pressure can worsen muscle necrosis and edema, and may even compress arteries, impairing blood supply and leading to compartment syndrome.
In addition, rhabdomyolysis may also cause hypovolemia and severe electrolyte imbalances. It is recommended to actively seek treatment under medical guidance to prevent disease progression.
