What are the consequences of long-term use of omeprazole?

Apr 15, 2023 Source: Cainiu Health

Dr. Wang Xuemei

Introduction

Omeprazole is a medication used to treat gastric ulcers, duodenal ulcers, and similar conditions. Long-term use may lead to gastrointestinal discomfort, anemia, impaired calcium absorption, atrophic gastritis, and liver damage. It is recommended to take this medication as directed by a physician. Omeprazole is not intended for long-term use. If symptoms do not improve after taking the medication, patients should seek medical attention promptly and adjust their treatment under a doctor's guidance.

Generally, omeprazole is a medication used to treat conditions such as gastric ulcers and duodenal ulcers. Long-term use may lead to gastrointestinal discomfort, anemia, impaired calcium absorption, atrophic gastritis, and liver damage. It is recommended to take this medication under medical supervision. Specific analyses are as follows:

1. Gastrointestinal discomfort

Long-term use of omeprazole may cause excessively reduced gastric acid secretion, impairing digestion and leading to indigestion or intestinal flora imbalance, which can result in bloating, diarrhea, and other discomforts.

2. Anemia

Omeprazole inhibits gastric acid secretion. Prolonged use may lead to insufficient gastric acid in the body, reducing iron absorption and causing symptoms of anemia.

3. Impaired calcium absorption

Long-term use of omeprazole may result in inadequate gastric acid, thereby reducing calcium absorption, increasing the risk of osteoporosis and fractures.

4. Atrophic gastritis

Prolonged use of the drug may damage the gastric mucosa, causing gastrointestinal system disorders and decreased gastric mucosal function, potentially progressing to atrophic gastritis, accompanied by symptoms such as nausea and vomiting.

5. Liver damage

Long-term medication use may disrupt the endocrine system, possibly leading to liver injury, reduced digestive function in the gastrointestinal tract, impaired nutrient absorption, and constipation.

Long-term use of omeprazole is not recommended. If symptoms persist despite taking the medication, patients should seek timely medical attention for evaluation and adjustment of treatment under a doctor's guidance. During treatment, maintaining a light diet can reduce the burden on the gastrointestinal system and support recovery.

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