What does it mean if creatinine is high in a urine test?

Apr 16, 2023 Source: Cainiu Health
Dr. Zhao Xinju
Introduction
High creatinine in urine tests may result from a transient increase in urinary creatinine due to elevated metabolic rates following intense physical activity within a short period of time. It could also be caused by decreased thyroid hormone secretion and reduced kidney excretory function, leading to increased creatinine levels in the urine. When unstable diabetes affects the kidneys, glomerular filtration rate increases, resulting in greater creatinine excretion and thus elevated creatinine levels detected in urine tests.

Under normal circumstances, elevated creatinine in urine tests may be caused by physiological factors or pathological conditions such as hypothyroidism and diabetic nephropathy. The specific analysis is as follows:

1. Physiological Factors

After intense physical exercise within a short period of time, the body's metabolic rate increases, leading to an increased glomerular filtration rate. This can result in a transient elevation of urinary creatinine. Symptoms typically improve with adequate rest.

2. Pathological Factors

1) Hypothyroidism

Due to reduced secretion of thyroid hormones, sodium metabolism in the body increases and kidney excretory function weakens, which may also lead to elevated creatinine levels in urine tests. It is recommended to take medications such as levothyroxine sodium tablets or thyroid tablets under medical guidance to promote thyroid hormone secretion and improve symptoms.

2) Diabetic Nephropathy

When unstable diabetes affects the kidneys, damage to the kidneys leads to an increased glomerular filtration rate. As more creatinine is excreted, urine tests will show elevated creatinine levels. It is recommended to take medications such as acarbose tablets, metformin hydrochloride sustained-release tablets, and beraprost sodium tablets under medical supervision to control blood glucose, inhibit platelet activation, and improve microcirculation, thereby managing symptoms.

In addition, elevated urinary creatinine could also be caused by uremia. If symptoms persist for a prolonged period or are accompanied by other discomforts, timely medical consultation and treatment are advised.


Related Articles

View All