What is the difference between progesterone and estradiol?

May 04, 2023 Source: Cainiu Health
Dr. Lv Aiming
Introduction
Differences between progesterone and estradiol include their functions, properties, and sources. Progesterone inhibits excessive endometrial proliferation, thins the endometrium, and prevents endometrial lesions; estradiol promotes endometrial growth and repair. Progesterone is a progestogen; estradiol is a steroid estrogen. Progesterone is primarily produced by the ovaries; estradiol is mainly secreted by the ovaries and adrenal glands.

       The differences between progesterone and estradiol include their functions, properties, sources, and more. A detailed analysis is as follows:

  1. Function

  Progesterone can inhibit excessive proliferation of the endometrium, thin the endometrial lining, and prevent endometrial lesions; estradiol primarily promotes endometrial growth and repair.

  2. Properties

  Progesterone is a progestogen and is an essential hormone for maintaining pregnancy; estradiol is a steroid estrogen that plays an important role in female development.

  3. Sources

  Progesterone is mainly produced by the ovaries, with daily production of 2–3 mg before ovulation and increasing to 20–30 mg per day after ovulation; estradiol is primarily secreted by the ovaries and adrenal glands.

  In addition, the two hormones also differ in how they exert their effects. Any abnormality in either hormone requires medical consultation, thorough examination, and identification of the underlying cause.

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