Is an alpha-fetoprotein level of 15 μg/L severe?

May 04, 2023 Source: Cainiu Health
Dr. Jiang Weimin
Introduction
An alpha-fetoprotein (AFP) level of 15 μg/L falls within the normal range. Alpha-fetoprotein is normally present at relatively high concentrations in fetal circulation; after birth, it is largely replaced by albumin, leading to a decrease in blood concentration. In adults, serum AFP levels further decline and are typically less than 25 μg/L. Therefore, an AFP measurement of 15 μg/L is considered normal.

An alpha-fetoprotein (AFP) level of 15 μg/L falls within the normal range and is generally not a cause for concern, typically requiring no treatment. The detailed explanation is as follows:

Alpha-fetoprotein is a glycoprotein primarily synthesized by fetal liver cells and the yolk sac. It is normally present at high concentrations in fetal circulation. After birth, AFP is largely replaced by albumin, leading to a significant decrease in blood concentration. In adults, serum AFP levels further decline and are normally less than 25 μg/L. Therefore, an AFP measurement of 15 μg/L is considered within the normal range.

In daily life, it is recommended to undergo regular health check-ups to detect potential issues early and allow timely medical intervention if necessary.


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