What causes small, itchy blisters on the hands followed by dryness, cracking, and peeling? What should be done about it?

May 05, 2023 Source: Cainiu Health
Dr. Liu Wan
Introduction
Small, itchy blisters on the hands accompanied by dryness, cracking, and peeling may be pompholyx (dyshidrotic eczema), which can be treated with topical medications such as triamcinolone acetonide acetic acid and urea ointment or hydrocortisone butyrate cream. They could also indicate keratolysis exfoliativa, which can be managed with topical salicylic acid ointment or urea cream. Additionally, these symptoms might be caused by eczema. Always follow medical advice when using medications.

In general, small itchy blisters on the hands accompanied by dryness, cracking, and peeling may be caused by conditions such as dyshidrotic eczema, keratolysis exfoliativa, or eczema, which require symptomatic treatment. Specific analyses are as follows:

1. Dyshidrotic Eczema

Dyshidrotic eczema is usually associated with localized skin allergies, fungal infections, and other factors. Main symptoms include blisters and itching; after the blisters dry up, scaling may occur. Patients can follow medical advice to apply topical medications such as triamcinolone acetonide acetate urea ointment or hydrocortisone butyrate cream. Personal hygiene should be maintained in daily life.

2. Keratolysis Exfoliativa

Keratolysis exfoliativa may be related to fungal infection, genetics, emotional factors, etc. Main symptoms include scaling and peeling; some patients may experience mild itching or a burning sensation. Patients can follow medical advice to apply topical medications such as salicylic acid ointment or urea cream. Eating more fresh vegetables and fruits in daily life is also recommended.

3. Eczema

Eczema is an inflammatory condition affecting the superficial dermis and epidermis, triggered by various internal and external factors. Main symptoms include small papules, blisters, and itching; as the blisters gradually dry, desquamation may occur. Patients can take oral medications such as diphenhydramine hydrochloride tablets or levocetirizine hydrochloride tablets as directed by a physician. It is important not to scratch the affected area to avoid worsening symptoms.

Additionally, these symptoms could also result from tinea manuum (hand fungus), contact dermatitis, or other causes. Patients are advised to seek timely medical evaluation at a hospital.


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